Research Reflections: Ep. 2 | Vegan v. Omnivore for Cholesterol

In nutrition research and, especially, in cardiovascular research there is quite a heated debate between vegan and omnivorous diets. In 2023, the headlines looked dramatic and conclusive:

“Twin research indicates that a vegan diet improves cardiovascular health”

In this episode, Dr. Alex Verge and I sit talk about how this particular study doesn’t quite live up to the hype. We also discuss:

  • What accounts for the weight change and insulin results that were seen

  • How not maintaining macro composition hindered the findings

  • Why diversity in the diet was a factor that confused results

  • The importance of diet satisfaction in long-term health managament

The study we discussed:

Cardiometabolic Effects of Omnivorous vs. Vegan Diets in Identical Twins

Landry MJ, Ward CP, Cunanan KM, Durand LR, Perelman D, Robinson JL, Hennings T, Koh L, Dant C, Zeitlin A, Ebel ER, Sonnenburg ED, Sonnenburg JL, Gardner CD. Cardiometabolic Effects of Omnivorous vs Vegan Diets in Identical Twins: A Randomized Clinical Trial. JAMA Netw Open. 2023 Nov 1;6(11):e2344457. doi: 10.1001/jamanetworkopen.2023.44457. Erratum in: JAMA Netw Open. 2023 Dec 1;6(12):e2350422. doi: 10.1001/jamanetworkopen.2023.50422. PMID: 38032644; PMCID: PMC10690456.

More on cardiovascular health:


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Research Reflections: Ep. 1 | Olive oil + All Cause Mortality